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논문 기본 정보

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(University of Minnesota) (University of Minnesota) (University of Minnesota) (University of Minnesota) (University of Minnesota) (University of Minnesota) (University of Minnesota)
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한국자기학회 한국자기학회 학술연구발표회 논문개요집 ICAUMS 2010
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    초록·키워드

    Bioassays that detect and quantify biomolecules at ultra-low quantity, with point of care settings, are of great need in personal medicine. Since the late 1990s, magnetoelectronics including giant magnetoresistive (GMR) sensor has emerged as one promising platform for biomolecule detection. We herein report the development of a novel detection system based on highly sensitive GMR sensor and sub-13 nm high-magnetic-moment FeCo nanoparticles, and the usefulness of this system for quantificating interleukin 6 (IL-6), a potential lung cancer biomarker, with extremely low concentration down to 150 copies per sensor surface. Magnetic label with high magnetic moment is preferred for the sake of generating larger magnetic signal, thereby higher sensitivity for the entire detection system. Furthermore, micro and sub-micro sized magnetic labels are not favorable for biomolecule detection due to the low diffusivity and poor binding selectivity. Recently, our group has successfully demonstrated the application of high moment FeCo magnetic nanoparticles with GMR biosensor. At ... 전체 초록 보기

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      UCI(KEPA) : I410-ECN-0101-2012-428-004107112