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논문 기본 정보

저자정보
(Seoul National University) (Seoul National University) (Seoul National University) (Seoul National University)
저널정보
한국생물공학회 한국생물공학회 학술대회 2011년도 한국생물공학회 춘계학술발표대회
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    초록·키워드

    Previous experimental and simulated results reported that mutations of protein cavity could improve the thermal stability. Many comparative studies between thermophilic and mesophilic proteins have been conducted to understand which cavity properties were related to the protein thermostability. However, previous statistical studies compared simple one dimensional information of cavities, e.g., surface area, volume, number of cavity and did not identify important differences of cavity properties between thermophilic and mesophilic proteins responsible for protein thermostability. In this study, we attempted to investigate the role of cavity properties in protein thermostability using three dimensional information of cavity properties. Protein struc ... 전체 초록 보기

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