인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Fucoidans are sulphated polysaccharides having L-fucose as major constituent. For the past decade fucoidans isolated from various species have been extensively studied due to their numerous biological activities, including antitumor and immunomodulatory, antivirus, anticoagulant and antithrombotic, anti-inflammatory, antioxidant and and many more. However, the effect of different sizes of fucoidan on melanin synthesis has not been elucidated yet. Therefore, the aim of the present study is to identify the skin whitening effect of the fucoidans in respect to molecular weights. To confirm the depigmenting effect of the native and the acid hydrolyzed fucoidan fractions, from Fucus vesiculosus were subjected to B16F10 melanoma and melan-a melanocyte cell line. The Cell viability (MTT) and melanin production were evaluated to elucidate the effect of fucoidan on depigmentation. The results showed that the crude fucoidan isolated from Fucus vesiculosus exhibited the melanin inhibition effect without cell toxicity up to the concentration 100 ug/ml in both cells. The purification of the hydrolyzed fractions required prior to establish the size effect of fucoidan on depigmentation. We anticipate the use of the fucoidan in different Cosmec ... 전체 초록 보기
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.