인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
학술저널
DBpia Top 10%
오류 신고하기해당 페이지 내 제목·저자·목차·페이지정보가 잘못된 경우 알려주세요!
초록·키워드
This study aimed to investigate effects of a mixture of Liriope platyphylla (LP) root and Lycium chinense (LC) fruit extract on NO production, gene expression of proinflammatory cytokines and chemokines, and inflammatory protein expression in Raw264.7 cells. Three mixtures of extracts were used, including LP:LC=1:1, LP:LC=5:1, LP:LC=10:1. Cells were treated with extracts at concentrations of 12.5, 25, and 50 μg/mL. In LPS-induced inflammation, a 1:1 mixture of LP extract and LC extract significantly inhibited NO production at a concentration of 50 μg/mL. All concentrations of the mixture reduced gene expression of the proinflammatory cytokines such as interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α except for the mixture of 10:1 at 12.5 μg/mL on TNF-α. They also reduced gene expression of chemokines such as monocyte chemoattracted protein (MCP)-1, macrophage inflammatory protein (MIP)-1α, as well as expression of the inflammatory protein cyclooxygenase (COX)-2. Among all tested combinations, the 1:1 mixture of LP extract and LC extract demonstrated a significant anti-inflammatory effect. These results suggest that the anti-inflammatory effects of the mixture of Liriope platyphylla (LP) root and Lycium chinense (LC) fruit extracts have the potential to be used as a composite mixture for the development of functional food.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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UCI(KEPA) : I410-151-25-02-091063409