인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
학술저널
Full-text XML
오류 신고하기해당 페이지 내 제목·저자·목차·페이지정보가 잘못된 경우 알려주세요!
피인용 0
초록·키워드
Background: Cellular oxidative damage caused by reactive oxygen species, byproducts of intracellular metabolic processes, is considered a major causal factor of aging. Many anti-oxidant molecules have been studied for their anti-aging and lifespan-extending effects in various model organisms ranging from yeast to mice.
Methods and Results: This study examined the effects of red ginseng extract on the stress response, lifespan, and age-related diseases using Caenorhabditis elegans as a model system. Red ginseng extract shows anti-oxidant activity in vitro and in vivo. Resistance to heat stress and ultraviolet irradiation was also significantly enhanced by red ginseng extract. Treatment with a 1/10 dilution of red ginseng extracts increased the mean and maximum lifespans without reducing fertility, which is frequently observed in many lifespan-extending interventions. In a genetic model of Parkinson’s disease, red ginseng extract completely blocked the degeneration of dopaminergic neurons and decreased alpha-synuclein expression.
Conclusions: Red ginseng extracts have anti-stress and lifespan-extending effects, and can reduce the risk of Parkinson’s disease. These findings suggested that red ginseng is a strong candidate for the development of novel nutriceuticals against aging and Parkinson’s disease.
Methods and Results: This study examined the effects of red ginseng extract on the stress response, lifespan, and age-related diseases using Caenorhabditis elegans as a model system. Red ginseng extract shows anti-oxidant activity in vitro and in vivo. Resistance to heat stress and ultraviolet irradiation was also significantly enhanced by red ginseng extract. Treatment with a 1/10 dilution of red ginseng extracts increased the mean and maximum lifespans without reducing fertility, which is frequently observed in many lifespan-extending interventions. In a genetic model of Parkinson’s disease, red ginseng extract completely blocked the degeneration of dopaminergic neurons and decreased alpha-synuclein expression.
Conclusions: Red ginseng extracts have anti-stress and lifespan-extending effects, and can reduce the risk of Parkinson’s disease. These findings suggested that red ginseng is a strong candidate for the development of novel nutriceuticals against aging and Parkinson’s disease.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
최근 본 자료 전체보기
UCI(KEPA) : I410-151-25-02-091264988
