인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Natural Korean medicine has already been a great success, being used to treat various types of othopedic diseases, especially fracture and osteoporosis. In this study, we find a new mixture of herbal medicine (JGT 2.0) of five well-known Korean herbal medicine for bone healing, including Angelica gigas, Dendrobium moniliforme, Dipsaci Radix, Antler, Astragalus membranaceus, Conidium officinale, Achyranthes japonica, Messa medicate fermentata on bone fracture healing. To evaluate the efficacy of JGT 2.0, the ulna of Sprague-Dawley rats was intentionally fractured and administered JGT 2.0, followed by radiographic imaging and histological examination using H&E staining to confirm the progress of recovery over time at the fracture site. X-ray imaging showed no significant difference between groups up to 1 week after JGT 2.0 administration. However, after 4 weeks of JGT 2.0 administration, bone regeneration decreased by -15% in the control group, but increased by 23.6% in the JGT 2.0 group. In addition, the length of calluses increased by 252% in the JGT 2.0 group compared to the control group. Taken together, the results suggest that JGT may offer a novel therapeutic approach to accelerate the growth of bone calluses and promote healing of bone fractures.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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UCI(KEPA) : I410-151-25-02-092318654