인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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초록·키워드
Background: Scutellaria baicalensis is a traditional medicinal plant that is rich in bioactive flavonoids, the accumulation of which can be impacted by environmental factors, including salinity. We aimed to determine the effects of different sodium chroride (NaCl) concentrations on the growth, flavonoid biosynthesis, and antioxidant activity of S. baicalensis hairy root cultures.
Methods and Results: We examined the effects of NaCl at various concentrations (0, 30, 50, 100, 200, and 300 mM) on biomass production, flavonoid content, and antioxidant properties of S. baicalensis hairy roots and found that biomass production was impaired by salinity, with 50 mM NaCl significantly reducing the biomass. High performance liquid chromatography of flavonoids at different salinity levels indicated high levels of baicalin, baicalein, and wogonin at an NaCl concentra- tion of 100 mM (moderate salinity-induced metabolic activation). Flavonoid synthesis was inhibited under high salinity conditions (200 mM - 300 mM NaCl); under these conditions, some flavonoids were undetectable. Higher radical scavenging and redox potentials were detected at an NaCl concentration of 100 mM, with lower IC<sub>50</sub> values in DPPH and ABTS, and reducing power antioxidant assays (compared to control conditions).
Conclusions: These results emphasize the importance of moderate salt stress in promoting bioactive compound production by S. baicalensis, providing information on its potential for cultivation under stress-adapted conditions and practical applications for medical use.
Methods and Results: We examined the effects of NaCl at various concentrations (0, 30, 50, 100, 200, and 300 mM) on biomass production, flavonoid content, and antioxidant properties of S. baicalensis hairy roots and found that biomass production was impaired by salinity, with 50 mM NaCl significantly reducing the biomass. High performance liquid chromatography of flavonoids at different salinity levels indicated high levels of baicalin, baicalein, and wogonin at an NaCl concentra- tion of 100 mM (moderate salinity-induced metabolic activation). Flavonoid synthesis was inhibited under high salinity conditions (200 mM - 300 mM NaCl); under these conditions, some flavonoids were undetectable. Higher radical scavenging and redox potentials were detected at an NaCl concentration of 100 mM, with lower IC<sub>50</sub> values in DPPH and ABTS, and reducing power antioxidant assays (compared to control conditions).
Conclusions: These results emphasize the importance of moderate salt stress in promoting bioactive compound production by S. baicalensis, providing information on its potential for cultivation under stress-adapted conditions and practical applications for medical use.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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