인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Horse oil contains up to 65% unsaturated fatty acids and protects human skin from environmental stressors. This study was performed to investigate the stability and protective effects of nano-sized horse oil-in-water (HO/W) emulsions, including emulsions enhanced with α-tocopherol (HO/W+α-T) or trolox (HO/W+T), against particulate matter (PM)-induced oxidative stress in HaCaT human keratinocytes. Mean particle diameters in these HO/W emulsions ranged from 154.5 to 169.2 nm, classifying them as nano-sized emulsions. The encapsulation efficiencies of HO/W and HO/W+α-T were 89.98-90.79%. The HO/W, HO/W+α-T, and HO/W+T emulsions sufficiently reduced lactate hydrogenase (LDH) release in HaCaT cells that has been exposed to 62.5 mg/mL of PM. The HO/W+α-T emulsion also significantly inhibited PM-induced lipid peroxidation. These results demonstrate that the horse oil O/W emulsion exhibits cytoprotective effects by inhibiting lipid peroxidation and increasing the viability of PM-exposed HaCaT cells, suggesting its potential as a novel strategy for preventing skin damage caused by environmental pollutants.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
최근 본 자료 전체보기
UCI(KEPA) : I410-151-25-02-092315582