인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
It has been well known that the differences in the structure and function of connective tissues, including tendon and ligament can have a significant impact on the sports performance of athletes. Thus, in this study, we attempted to analyze whether single nucleotide polymorphism(SNP) markers in a total of four candidate genes such as rs1800012 polymorphism in collagen type I α1 chain(COL1A1) gene, rs12722 polymorphism in collagen type V α1 chain(COL5A1) gene, rs679620 polymorphism in matrix metalloproteinase 3(MMP3) gene and rs143383 polymorphism in growth and differentiation factor 5(GDF5) gene known to affect connective tissue characteristics and injuries have a significant influence on the athletic performance of kendo players. A total of 110 subjects including 35 controls and 75 kendo players were participated in this study, and genotyping on each SNP marker in a total of four candidate genes performed by SNaPshot method. Among four SNP markers, a rs679620 polymorphism in MMP3 gene was significantly associated with the athletic performance of kendo players, and especially, GG genotype and G allele indicated the significantly higher frequencies in kendo players than controls, respectively(p < .05). In the future, if extended studies are conducted to confirm whether this genetic polymorphism can show a significant association with other martial art disciplines, it is expected that interesting study results can be derived.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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UCI(KEPA) : I410-151-25-02-092450460