인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Bee venom (BV) consists of various bio-actives, including proteins, peptides, enzymes, and volatile metabolites. Over the last decade, the antimicrobial effect of BV against bacterial pathogens has been demonstrated through various in vitro and in vivo experiments. Because mastitis has a serious impact on the dairy industry, the present study aimed to evaluate the antibacterial activity of BV against multidrug-resistant S. aureus and E. coli, which are difficult to treat using antibiotics. In this study, 25 E. coli and 15 S. aureus strains from bovine mastitis were used for BV MIC testing. Based on the antibiotic resistance pattern, all isolates were categorized into three groups: susceptible, resistant, and multidrug-resistant. BV MICs for the E. coli and S. aureus isolates ranged from 16 -128 μg/mL and 16-32 μg/mL, respectively. There were no significant differences between the antibiotic resistance and BV MICs of the isolates. However, two multidrug resistance (AMP-CEF-OXA-PEN) S. aureus isolates showed 2-fold higher BV MIC values than the other S. aureus isolates. Therefore, BV can be used as an adjunct treatment for mastitis caused by antibiotic-resistant bacteria. Further studies are needed to understand the resistance mechanisms of multidrug-resistant bacteria, and in vivo studies are required to evaluate the efficacy and safety of BV.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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UCI(KEPA) : I410-151-25-02-093732416