인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
피인용 0
초록·키워드
This study was conducted to investigate the antibacterial activity of Nigella sativa seed oil (HT_01) against several oral pathogens and the inhibitory effects of HT_01 on acid production and biofilm formation in Streptococcus mutans. The antibacterial activity of HT_01 was tested using the disk diffusion and microdilution methods according to Clinical & Laboratory Standards Institute and Korean Ministry of Food and Drug Safety guidelines. The acid-producing ability test and biofilm formation ability were performed according to Korean Ministry of Food and Drug Safety guidelines. The inhibition zone around the disks containing 50 μL of 10% HT_01 were 42.5 ± 2.5 mm for S. mutans, 41.4 ± 4 mm for Porphyromonas gingivalis, 45 ± 3 mm for Prevotella intermedia, and 28 ± 3 mm for Fusobacterium nucleatum, indicating a strong antibacterial effect. Analysis of acid production showed that the pH of culture broth of S. mutans was 4.23 ± 0.05, whereas culture broth containing of 0.04% and 0.05% HT_01 had neutral pH values of 7.35 ± 0.02 and 7.21 ± 0.04, respectively, confirming the inhibition of acid production. Compared with the control group considered as showing 100% biofilm formation, the rate of biofilm formation was only 32% in the presence of 0.05% HT_01. HT_01 showed potent antibacterial activity against oral pathogens. HT_01 showed potent inhibitory activity against acid production and biofilm formation in S. mutans.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
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UCI(KEPA) : I410-151-26-02-094380813
