인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
피인용 0
초록·키워드
Quercus acuta Thunb. (Q. acuta) is a subtropical, evergreen, broad-leaved tree with excellent carbon sequestration capacity and ecological adaptability. However, the phytochemical composition of fruits, particularly phenolic marker compounds, has not been sufficiently investigated. In this study, the biological activities of water and ethanol extracts of Q. acuta fruits were evaluated, and a high-performance liquid chromatography with diode array detection (HPLC-DAD)-based method for the quantification of marker compounds was established and validated. MTT assays showed no cytotoxicity at concentrations of 5–20 μg/mL, and the water extract significantly inhibited UVB-induced MMP-1 expression in HaCaT keratinocytes. Gallic acid and ellagic acid in Q. acuta fruits were confirmed as marker compounds, and the validated method demonstrated excellent linearity (R² > 0.999), recovery, and precision (RSD < 2.0%). Quantitative analysis revealed that the water extract contained higher levels of phenolic compounds compared with the 70% and 100% ethanol extracts. These findings support the stability and biological efficacy of phenolic marker compounds in aqueous environments and suggest the potential industrial applications of Q. acuta fruit extracts.
본문·목차
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UCI(KEPA) : I410-151-26-02-095630974
