인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
피인용 0
초록·키워드
Actinidia arguta (A. arguta, Korean darae) is widely distributed as a major nectar and pollen source, and its bee pollen is known to be the most widely produced monofloral bee pollen in Korea. Phenolamides identified in bee pollen have been reported to exhibit beneficial biological functions in humans. Among them, N¹,N<sup>5</sup>,N<sup>10</sup>-tri-p-coumaroylspermidine (TPCS) has been associated with antioxidant, anti-inflammatory, and photoprotective activities. However, the purification of TPCS has traditionally been carried out through laborious and time-consuming chromatographic procedures, resulting in low yields and limited reproducibility. Herein, a simple and efficient approach was developed for the isolation and identification of TPCS from A. arguta bee pollen. The methanolic extract was fractionated by MPLC, followed by Sephadex purification. The purified compound was identified as TPCS based on UPLC, LC-Q-TOF/MS, and NMR analyses. Furthermore, to explore the potential biological relevance of TPCS, molecular docking analysis was performed against polo-like kinase 1(PLK1), which showed a stable binding interaction. This work provides new insights into the phenolamide composition of A. arguta bee pollen and establishes a practical method for the efficient isolation of TPCS from natural sources, thereby supporting future biochemical and pharmacological studies.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
최근 본 자료 전체보기
UCI(KEPA) : I410-151-26-02-096395634
