메뉴 건너뛰기
소속 기관 / 학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
고객센터 ENG
주제분류

논문 기본 정보

저자정보
(Korea Institute of Oriental Medicine) (Korea Institute of Oriental Medicine) (Korea Institute of Oriental Medicine) (Hannam University) (Hannam University)
저널정보
한국식품과학회 한국식품과학회지 한국식품과학회지 제58권 제1호
오류 신고하기

피인용 0

검색

    초록·키워드

    Bambusae Caulis in Taeniam (BCT) has traditionally been used to relieve vomiting, febrile symptoms, and mucosal irritation, whereas its anti-allergic mechanisms remain poorly understood. In this study, the anti-allergic activity of BCT was assessed in vivo using the passive cutaneous anaphylaxis (PCA) model and in vitro using MC/9 mast cells. Oral administration of BCT significantly reduced Evans blue extravasation in PCA mice, indicating inhibition of immunoglobulin E (IgE)-mediated immediate hypersensitivity. In MC/9 cells, BCT dose-dependently suppressed PMA/A23187-induced secretion of histamine, prostaglandin E2 (PGE2), and tumor necrosis factor-α (TNF-α). Mechanistically, BCT inhibited the phosphorylation of mitogen-activated protein kinases (JNK, ERK, and p38) and reduced nuclear factor κB (NF-κB) mRNA expression. These findings suggest that BCT mitigates immediate allergic responses by modulating mast cell activation and key inflammatory signaling pathways, supporting its potential as a natural anti-allergic agent.

    최근 본 자료 전체보기

      UCI(KEPA) : I410-151-26-02-096391814