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논문 기본 정보

자료유형
학술저널
저자정보
(Kyungpook National University) (Kyungpook National University) (Kyungpook National University) (Kyungpook National University) (Kyungpook National University) (Sookmyung Women’s University) (Chosun Univsersity) (Kyungpook National University)
저널정보
한국식품과학회 Food Science and Biotechnology Food Science and Biotechnology vol 16. no 4
발행연도
수록면
641 - 645 (5page)

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초록· 키워드

Delphinidin, an aglycone form of anthocyanins, was demonstrated to have anti-carcinogenic potential. The compound at 50 μg/mL caused a significant increase of quinone reductase activity, an anti-carcinogenic marker enzyme, in mouse hepatoma cell lines (Hepa1c1c7 and BPRc1). Delphinidin enhanced the expression of other detoxifying or antioxidant enzymes including glutathione S-transferase, gamma-glutamylcysteine synthetase, heme oxygenase 1, and glutathione reductase. It suppressed the proliferation of murine hepatoma cells in a dose-dependent manner, with approximately IC<sub>50</sub> of 70 μg/mL. These results suggest that delphinidin might be useful for cancer prevention.
#delphinidin #antioxidant #cancer prevention #quinone reductase
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목차

  1. Abstract
  2. Introduction
  3. Materials and Methods
  4. Results and Discussion
  5. Acknowledgments
  6. References

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UCI(KEPA) : I410-ECN-0101-2013-573-001023359