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논문 기본 정보

저자정보
(동신대학교) (동신대학교) (빛가람 생명농업공동체 협동조합) (동신대학교)
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한의병리학회 동의생리병리학회지 동의생리병리학회지 제29권 제3호
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피인용 2

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    초록·키워드

    In this study, we used the mixture made from the Rice bran 45 ㎏, Dendropanax 5 ㎏, the sugar of the 10% of the total weight, and the enzyme of the 0.1% of the total weight. After the mixture were fermented for 90 days under 20 ℃, we measured the cell viability and the inhibition rate of the melanin biosynthesis, the activity of tyrosinase and superoxide dismutase (SOD) in malignant melanoma, B16F10 cells, in order to survey the whitening effect and the mechanism of the effects on the sample. As a result, the samples significantly suppressed the cell viability of B16F10 in more than 500 ㎍/㎖ and significantly inhibited the generation of melanin induced by α-MSH in more than 1,000 ㎍/㎖. Sample decreased the activity of tyrosinase while increased the activity of SOD in dose dependent manner. Therefore, we considered that the fermentation extract made from a Rice bran and Dendropanax will be able to produce high value-added products, if used as a commercial.

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      UCI(KEPA) : I410-ECN-0101-2016-519-001712697