인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
학술저널
Full-text AI
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피인용 0
초록·키워드
This study was performed to select adequate plant materials for developing a natural α-glucosidase inhibitor by analyzing α-glucosidase inhibition activity in fronds and rhizomes of three Dryopteridaceae species: Cyrtomium fortunei, Polystichum polyblepharum, and P. lepidocaulon. The highest α-glucosidase inhibitor obtained from frond of P. lepidocaulon (4.16㎍ · mL<sup>-1</sup>), and rhizome of C. fortunei (1.84㎍ · mL<sup>-1</sup>), showed much higher inhibition activity than acarbose (1413.70㎍ · mL<sup>-1</sup>). The biomass required to inhibit α-glucosidase by 50% was 0.04 ~ 0.35㎎ for frond and 0.03 ~ 0.10㎎ for rhizome, and P. lepidocaulon required the least amount of fronds and P. lepidocaulon the least rhizomes. In frond, α-glucosidase inhibition activity was the highest in water fraction of C. fortunei (20.2㎍ · mL<sup>-1</sup>), and n-butanol fraction of P. lepidocaulon (9.33㎍ · mL<sup>-1</sup>) and P. polyblepharum (5.10㎍ · mL<sup>-1</sup>). In rhizome, it was the highest in n-butanol fractions of C. fortunei (19.76㎍ · mL<sup>-1</sup>) and P. polyblepharum (4.47㎍ · mL<sup>-1</sup>), and ethylacetate fraction of P. lepidocaulon (5.46㎍ · mL<sup>-1</sup>). The frond biomass required for 50% α-glucosidase inhibition was the lowest in the water fraction of C. fortunei (1.43㎎), and n-butanol fractions of P. lepidocaulon (1.10㎎) and P. polyblepharum (0.66㎎). The required biomass of rhizome was the lowest in the water fraction of C. fortunei (1.59㎎), and n-hexane fractions of P. lepidocaulon (0.04㎎) and P. polyblepharum (0.15㎎). The result of this study suggested that the three Dryopteridaceae species had high α-glucosidase inhibition activity with small biomass, which might have high value as materials for economical anti-diabetic medication.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
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최근 본 자료 전체보기
UCI(KEPA) : I410-ECN-0101-2019-480-000587532
