인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
학술저널
Full-text AI
오류 신고하기해당 페이지 내 제목·저자·목차·페이지정보가 잘못된 경우 알려주세요!
초록·키워드
This study was indicated to enhance the anti-inflammation activities by the fermentation of the fruits of Aroniamelanocarpa (Michx.) Elliott. The extracts by 70% ethanol (EE) showed better biological activities than those by hotwater (WE) from campared result of the effect of extraction solvents. Then, the extract from 70% ethanol extraction wasfurther fermented by lactic acid, denoted as FEE. For antioxidant activities, the FEE had showed the highest value as 0.832of reducing powder, in comparison with those of EE and WE. Cytotoxicity of the water extraction (WE) was measured for12.06% in addition of 1.0 ㎎/㎖ of FEE. For anti-inflammation activities, NO production from the macrophage, RAW 264.7was observed as 7.24 μM and 8.52 μM from FEE and EE, respectively. Prostaglandin E2 (PGE₂) production from humanfibroblast cell, CCD-986sk, was also estimated for 152 pg/㎖ in addition of 1.0 ㎎/㎖ of the FEE. The lowest production ofboth IL-6 and TNF-α were 3.5 pg/㎖ and 865.5 pg/㎖, respectively in addition of 1.0 ㎎/㎖ of the FEE, whereas 74.5 pg/㎖and 982.4 pg/㎖ in treated with same concenrations of the EE. It was also found that the FEE was higher amounts thanother extracts through HPLC analysis of the anthocyanins. These results strongly indicate that fermentation process of thelactic acid could enhance anti-inflammation activities of extracts by increasing the amounts of the anthocyanins, especiallycyanidin-galactoside. Our results suggest that the application of the fermentation process for other medicinal herbs can beimproved their biological activities.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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UCI(KEPA) : I410-ECN-0101-2019-480-000587921