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    초록·키워드

    Methanolic and aqueous extracts of 26 red algae species collected from Jeju Island coast were prepared at a high (70℃) and a room temperature (20℃) and were examined for their cytotoxic activity against 4 tumor cell lines: U-937 (human monoblastoid leukemia cell line), HL-60 (human promyelocytic leukemia cell line), B-16 (murine melanoma cell line) and HeLa (woman cervical carcinoma cell line). 20℃ methanolic extract of Polysiphonia japonica showed cytotoxic activity of over 50% against U-937, HL-60 and B-16 cells. On the other hand, the 20℃ aqueous extract of Scinaia okamurae and 70℃ aqueous extract of Chondrus crispus showed cell growth inhibition activity of more than 50% against HL-60 and B-16 cells. The highest cytotoxic activity was observed in the 20℃ aqueous extract of Scinaia okamurae against B-16 cells (80.55%).

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      UCI(KEPA) : I410-ECN-0101-2009-511-017343034