인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Myogenesis is one of critical developmental process in mammals. Whole body muscles are derived from the embryonic somites except some parts of head muscles. Two kinds of genes are affecting to embryonic myogenesis, which is the genes related patterning formation of myotomes and muscle specific transcription regulating genes. Among them, Dmrt2 which affects myotomal patterning formation, and Pax3 which regulates myogenic specific transcription, doubly mutants tested using the myogenin gene expression pattern in mice embryos. Myogenin gene expression pattern was severely malformed in doubly homozygous mutant and showed very low expression levels of myogenin. However even though doubly mutation was occurred, myogenin expressing cells were not completely abolished in myotomes at around embryonic day (E) 10.5. Every possible compounding genotype between two genes was examined and discussed about the function of each gene. These experiments would be helpful to understand myogenesis process in mammals, which is closely linked to muscle regeneration program after muscle injury in adult mammals.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
최근 본 자료 전체보기
UCI(KEPA) : I410-ECN-0101-2009-510-016362489