인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Recently, much attention has been focussed on the use of plant-based phytopharmaceuticals and phytonutrients for prevention or as adjuncts to conventional therapy. In conjunction with the current concern about the practice of complementary and alternative medicine for the management of a wide array of human disorders, the use of herbal medicine has been increasing worldwide. Numerous biologically active substances derived from herbs and spices have been reported to possess the therapeutic potential. The rapid progress in our understanding of the cellular signal transduction pathways thaat are subjected to fine-tuning has paved the way to unveiling the molecular milieu of cellular homeostasis. Our current research program concerns the evaluation of cancer chemopreventive and cytoprotective effect of some anti-inflammatory phytochemicals present in dietary and medicinal plants and their underlying molecular mechanisms. These include curcumin (Curcuma longa L., Zingiberaceae), [6]-gingerol (Zingiber officinale Roscoe, Zingiberaceae), capsaicin (Capsicum annum L., Solanaceae), eupatilline
(Artemia asiatica Nakai), and yakuchinone A and B (Alpinia oxyphylla Miquel, Zingiberaceae). All these phytochemicals have been found to exert chemopreventive
activities by blocking aberrant NF-kappaB signaling, which often occurs during inflammation-associated carcinogenesis. Alternatively, some phytochemicals, by inducing transcription of antioxidant genes, can potentiate cellular defence capacity against oxidative injury which is implicated in pathogenesis of many human ailments. Modulation of cellular signaling pathways thus represents an essential components of evidence-based chemoprevention of cancer and other malfunctions.
(Artemia asiatica Nakai), and yakuchinone A and B (Alpinia oxyphylla Miquel, Zingiberaceae). All these phytochemicals have been found to exert chemopreventive
activities by blocking aberrant NF-kappaB signaling, which often occurs during inflammation-associated carcinogenesis. Alternatively, some phytochemicals, by inducing transcription of antioxidant genes, can potentiate cellular defence capacity against oxidative injury which is implicated in pathogenesis of many human ailments. Modulation of cellular signaling pathways thus represents an essential components of evidence-based chemoprevention of cancer and other malfunctions.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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UCI(KEPA) : I410-ECN-0101-2013-573-000932848