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초록· 키워드
Pathogenesis of cow milk allergy indicates that multiple immunological mechanisms exist. Two types of food allergy reactions occur in infants, children and adults. They are reaginic (IgE-mediated) or nonreaginic. About 7% of children in the U.S. have symptoms of cow milk allergy, even though almost all children under age 3 have circulating milk antibodies. Beta-lactoglobulin (MW 36,000) is the major whey protein of cow milk, not found in human breast milk and mostly responsible for cow milk allergy. Clinical symptomology for patients allergic to bovine milk proteins include: rhinitis, diarrhea, vomiting, asthma, anaphylaxis, urticaria, eczema, chronic catarrh, migraine, colitis and epigastric distress. Goat milk has been recommended as substitute for patients allergic to cow milk. Between 40 to 100% of patients allergic to cow milk proteins tolerate goat milk. Although some caprine milk proteins have immunological crossreactivity with cow milk proteins, infants suffering from gastrointestinal allergy and chronic enteropathy against cow milk were reportedly cured by goat milk therapy. The higher protein, nonprotein N and phosphate in caprine milk give it greater buffering capacity compared to cow milk. Some physico-chemical properties of caprine milk such as smaller fat globules, higher percent of short and medium chain fatty acids, and softer curd formation of its proteins are advantageous for higher digestibility and healthier lipid metabolism relative to cow milk. Goat milk also has a greater iron bioavailability in anemic rats than cow milk. Further studies of the hypo-allergenic and therapeutic significance of goat milk to humans are very much needed.
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목차
- Introduction
- Pathogenesis of Food Allergy
- Clinical Manifestations of Cow Milk Allergy
- Hypo-Allergenicity of Goat Milk
- Therapeutic and Special Nutritional Merits of Goat Milk
- References
참고문헌
참고문헌 신청최근 본 자료
UCI(KEPA) : I410-ECN-0101-2013-573-001192862
