인문학
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자연과학
공학
의약학
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예술체육학
복합학
DBpia AI
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AI 아이디어
AI 리더
AI 뷰어
Citeasy
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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 저자정보
피인용 0
초록·키워드
The present study was carried out to investigate promotional effect of herbal extracts on hair growth in an animal model of mice. There were four experimental groups including distilled water (DW) as negative control (NC), 3% minoxidil (MXD) as positive control (PC), 50% ethanol (EtOH) as vehicle control (VC) and herbal extract (HE) as experimental treatment (E). The HE was extracted with ethanol from plants including Gardenia, Mentha arvensis, Rosemary, and Lavender. The 6 weeks-old C57BL/6 male mice were shaved with an electric clipper and the test materials were topically treated with 0.2 ml per mouse daily for 3 weeks. The hair re-growth was photographically evaluated weekly during 3 weeks. The number of mast cells was counted on the dorsal skin section of mice. The enzymes, alkaline phosphatase (ALP) and γ-glutamyl transpeptidase (γ-GT), were determined using an biochemical autoanalyzer. There were no clinical signs in all experimental groups. As the results of photometric analysis, the topical application of HE for 2 week to dorsal skin accelerated hair regrowth significantly faster than that of NC or VC group (P<0.05). PC and E groups showed a significant decrease in mast cell population compared to NC group. Activities of ALP and γ-GT were significantly increased in PC and E groups compared to NC or VC group (P<0.05). Taken together, these results suggest that the herbal extract may have hair-growth promoting activity equal to that of MXD.
본문·목차
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최근 본 자료 전체보기
UCI(KEPA) : I410-ECN-0101-2013-528-002902476
