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논문 기본 정보

저자정보
(Daegu Universtiy) (Daegu Universtiy)
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한국생물공학회 한국생물공학회 학술대회 2015 한국생물공학회춘계학술발표대회 및 국제심포지엄
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    초록·키워드

    Our previous study revealed that galectin-1 (GAL1) was up-regulated in obese rats, and thus we suggested that use of its inhibitors would be a novel therapeutic approach for the treatment of obesity. To this end, we used thiodigalactoside (TDG), a potent inhibitor of GAL1, in order to identify differentially expressed proteins in white adipose tissues (WAT) of rats. We have performed a comparative analysis of protein expression profiles of WAT of control and TDG-treated rats using 2-DE combined with MALDI-TOF-MS. Differential expression of 32 spots from a total of 356 matched spots were identified as WAT proteins altered between control and TDG-treated rats by peptide mass finger printing. On the basis of the roles of proteins which show differences in expression were categorized in some groups, including c ... 전체 초록 보기

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      UCI(KEPA) : I410-ECN-0101-2016-470-001528882