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논문 기본 정보

자료유형
학술저널
저자정보
(Catholic University)
저널정보
대한바이러스학회 JOURNAL OF BACTERIOLOGY AND VIROLOGY Journal of Bacteriology and Virology 제42권 제4호
발행연도
수록면
359 - 362 (4page)

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초록· 키워드

The revelation that gut microbes are associated with the pathogenesis of human diseases such as obesity, colon cancer, inflammatory bowel disease and liver-related diseases has resulted in the role of gut microbes becoming a novel research topic in basic and clinical science. Recently, emphasis has been placed on the role of gut microbes in non-alcoholic fatty liver disease (NAFLD) and its progressive form, non-alcoholic steatohepatitis (NASH). Researchers have suggested that inflammasome deficiency-changed dysbiosis is associated with exacerbating NAFLD/NASH progression. This particular study also showed a direct "gut-liver axis" regulated by modulation of gut microbiota. This paper (Nature 2012;482: 179-185) was summarized herein and the potential clinical applications were discussed.
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