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논문 기본 정보

자료유형
학술대회자료
저자정보
(포항공과대학교) (포항공과대학교) (포항공과대학교) (포항공과대학교)
저널정보
대한기계학회 대한기계학회 춘추학술대회 대한기계학회 창립 70주년 기념 학술대회
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3,157 - 3,160 (4page)

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초록· 키워드

Micro-scale topography fabrication have attracted much attention in biomedical engineering because of their potential for stem cell proliferation enhancement effect. In recent years, adult stem cells (ASCs) are proved as versatile troubleshooter in biomedical and pharmaceutical field. However, ASCs take up only a small proportion of somatic cells in human body and the study of enhancing the proliferation rate of ASCs became essential in modern society. Researchers suggested the use of topographic stimuli as solution for this problem. Numerous researches were executed to clarify the relationship of topography and ASCs proliferation but there are still difficulties in defining tendency to clearly deduce an optimal topography for enhancing proliferation rate due to an intervention of other factors. To overcome this weakness we propose a multi-well cell culture platform that allows simple way of screening effects of various kinds of topography on ASCs. In this study we fabricated multi-well cell culture platform containing micro-scale topography and carried out experiments of human Adipose derived Stem Cells (hASCs) proliferation. Through this experiment we verify the multi-well cell culture platform’s functionality then we expect that this multi-well cell culture platform system would contribute to finding optimal topography for enhancing ASCs proliferation rate.
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목차

  1. Abstract
  2. 1. Introduction
  3. 2. Materials and Methods
  4. 3. Results and Discussion
  5. 4. Conclusion
  6. 참고문헌

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UCI(KEPA) : I410-ECN-0101-2016-550-002167339