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자료유형
학술저널
저자정보
(Sungkyunkwan University) (Cheongju University) (Soongsil University) (Sungkyunkwan University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.41 No.4
발행연도
수록면
435 - 443 (9page)

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초록· 키워드

Panax ginseng is one of the most universally used herbal medicines in Asian and Western countries. Most of the biological activities of ginseng are derived from its main constituents, ginsenosides. Interestingly, a number of studies have reported that ginsenosides and their metabolites/derivativesdincluding ginsenoside (G)-Rb1, compound K, G-Rb2, G-Rd, G-Re, G-Rg1, G-Rg3, G-Rg5, G-Rh1, G-Rh2, and G-Rp1dexert anti-inflammatory activities in inflammatory responses by suppressing the production of proinflammatory cytokines and regulating the activities of inflammatory signaling pathways, such as nuclear factor-kB and activator protein-1. This review discusses recent studies regarding molecular mechanisms by which ginsenosides play critical roles in inflammatory responses and diseases, and provides evidence showing their potential to prevent and treat inflammatory diseases.
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  1. ABSTRACT
  2. 1. Introduction
  3. 2. Inflammatory responses and cytokines
  4. 3. Anti-inflammatory effects of ginsenosides
  5. 4. Conclusion
  6. References

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UCI(KEPA) : I410-ECN-0101-2018-524-001599175