인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
We evaluated the anti-wrinkle effects of Impatiens textori methanol extract (ITME). ITME treatment at 10 mg/mL decreased collagenase and elastase activity by 50.4% and 54.9%, respectively. In tests of human dermal fibroblast cytotoxicity, the maximum permissible level of ITME treatment was greater than 200 μg/mL. When compared to a control: i) treatment with 200 μg/mL of ITME significantly increased type I procollagen synthesis by 36.7% (p<0.05), and ii) treatment with 100 μg/mL ITME significantly decreased MMP-1 mRNA and protein expression by 23.1% and 35.3%, respectively (p< 0.01). Treatment with ITME resulted in a promotion of collagen synthesis and inhibition of collagen degradation in human dermal fibroblasts. Collectively, these results suggest that ITME could be used as functional cosmetic material to prevent or alleviate skin wrinkles induced by ultraviolet rays.
#항 주름 효과
#탄력소 활성
#물봉선
#Anti-wrinkle effects
#Elastase activity
#Impatiens textori
#MMP-1
#Type I procollagen
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