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사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
The purpose of the current study was to observe the effects of sandalwood oil (SO) on hair growth status changes asassessed by gross and histological analyses in a C57BL/6 mouse model of alopecia. C57BL/6 mice were randomized intoeither a normal group (N: saline), a positive control group (PC: 3% minoxidil), or an experimental group (E: 3% SO). SO(100 꺤L) was applied topically to the backs of mice once daily for 5 days a week over a 4-week period, and hair growthstatus changes were observed during 16 weeks. Study results revealed that the hair growth effect in the PC and E groupswas significantly greater as compared to the N group. At week 10, mice in the N group showed 13% hair loss as comparedto week 7, while mice in the both the PC and E groups showed 23% hair growth (both p.0.001). Hematoxylin and eosinstains were used for the histological analyses of skin tissues. During 16 weeks, hair follicle (HF) number, HF depth, anddermal thickness in the PC and E groups were significantly increased as compared to the N group. Additionally, thenumbers of mast cells in the PC and E groups at weeks 4 and 16 were significantly decreased as compared to the N group.
In conclusion, SO, like 3% minoxidil, promoted hair growth, maintained an anagen phase, and delayed the transition tothe catagen phase in a C57BL/6 mouse model of alopecia.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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