인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
.This study was conducted to know the changes of hair growth relevant factors including enzyme activity and cytokine expression by topical application of sandalwood oil to C57BL/6 mice. C57BL/6 mice were randomized into three groups consisting of normal group (N: saline), positive control group (PC: 3% minoxidil), and experimental group (E: 3% Sandalwood oil). Sandalwood oil(SO) was topically applied to the backs of mice with 100μL a day, once a day, 5 days a week, for 4 weeks, and the changes of hair growth relevant factors in mice skin were observed during 16 weeks. The alkaline phosphatase(ALP) activity in the PC and E groups was significantly higher(p⁄0.001) than that of the N group. The mRNA expression of hair growth promoting factors including prolactin(PRL) and vascular endothelial growth factor (VEGF) in the PC and E groups significantly(p⁄0.001) increased, compared to the N group. The mRNA expression of transforming growth factor-β1 (TGF-β1), hair growth inhibitory factor, in the PC and E groups was significantly decreased(p⁄0.001), compared to the N group. These results suggest that changes in values of growth related factors including ALP activity and mRNA expression of PRL, VEGF, and TGF-β1 are useful markers to represent the hair growth cycle.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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