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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 171 - 173 (3page)
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오류제보하기
Colchicine-induced leukopenia usually occurrs in intentional or accidental overdoses or inappropriate use in combination with intravenous and oral colchine; however, there have been several reports of hematologic toxicity in short-term and small-dose colchicine medication courses. We present two cases of leukopenia induced by colchicine use concurrent with immunosuppressants in Behçet's disease. We postulate that the mechanism of colchicine-induced leukopenia might be the destruction of circulating leukocytes and an inhibition of leukocyte production by the immediate and direct toxic effect of colchicine on idiosyncrasies unique to each patient. The concurrently administered immunosuppressant might decrease the threshold for hematologic toxicity of colchicine in the leukocytes and their precursor cells.
목차
등록된 정보가 없습니다.
참고문헌 (9)
참고문헌 신청
Andrews J / 2002 / Current management options in Behcet's disease / Minerva Med 93 : 335 ~ 345
Bello YM / 1998 / Management of venous ulcers / J Cutan Med Surg 3 (1) : 6 ~ 12
Ben-Chetrit E / 2003 / Colchicine-induced leukopenia in a patient with familial Mediterranean fever: the cause and a possible approach / Clin Exp Rheumatol 21 (4) : S38 ~ S40
Critchley JA / 1997 / Granulocyte-colony stimulating factor in the treatment of colchicine poisoning / Hum Exp Toxicol 16 : 229 ~ 232
Folpini A / 1995 / Colchicine toxicity clinical features and treatment. Massive overdose case report / Clin Toxicol 33 : 71 ~ 77
Bello YM / 1998 / Management of venous ulcers / J Cutan Med Surg 3 (1) : 6 ~ 12
Ben-Chetrit E / 2003 / Colchicine-induced leukopenia in a patient with familial Mediterranean fever: the cause and a possible approach / Clin Exp Rheumatol 21 (4) : S38 ~ S40
Critchley JA / 1997 / Granulocyte-colony stimulating factor in the treatment of colchicine poisoning / Hum Exp Toxicol 16 : 229 ~ 232
Folpini A / 1995 / Colchicine toxicity clinical features and treatment. Massive overdose case report / Clin Toxicol 33 : 71 ~ 77
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