메뉴 건너뛰기
소속 기관 / 학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
고객센터 ENG
주제분류

논문 기본 정보

저자정보
(Chonbuk National University) (Chonbuk National University) (Chonbuk National University)
저널정보
대한전자공학회 대한전자공학회 학술대회 2020년도 대한전자공학회 하계종합학술대회 논문집
오류 신고하기

검색

    초록·키워드

    DNA N4- methylcytosine (4mC) plays a crucial role in transcriptional regulation by repressing activity. DNA methylation takes part in many biological process such as Restriction –Modification(R-M) system, genomic imprinting, heredity performance, chromatin structure and suppression or repetitive sequences. In recent decades, computationally prediction of 4mC sites is much needed work in biomedical related fields. Experimental methods are costly and time-consuming so that we proposed a deep learning model to identify 4mc sits in the given DNA sequences. The previous method was developed by machine learning based method for identifying 4mC sites based on the handcrafted features while the proposed novel method extracts the features of the 4mC sites automatically using convolutional neural network (CNN). In this work, we applied the nucleotide chemical properties to encode the DNA sequences and fed those encoded sequences into the CNN model for the best feature selection and for the final classification whether the DNA sequence contains 4mC sites or not. The performance of the CNN model has been evaluated on the benchmark datasets and achieved generally good performance in predicting 4mC sites as compared to the previous method.

    본문·목차

    최근 본 자료 전체보기

      UCI(KEPA) : I410-ECN-0101-2020-569-001134194