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논문 기본 정보

저자정보
(Pusan National University) (Pusan National University) (Pusan National University) (Pusan National University) (Pusan National University) (Chungbuk National University) (Pusan National University)
저널정보
한국실험동물학회 한국실험동물학회 학술발표대회 논문집 2021년 한국실험동물학회 동계심포지엄 [초록집]
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    초록·키워드

    To investigate the effects of dysbiosis on fecal microbiota from C3 KO mice with constipation, the composition of fecal microbiota was characterized in transverse colons of 16-week-old C3 KO mice, and their function for defecation delay development was examined after fecal microbiota transplantation (FMT) of C3 KO mice. Some significant alterations in constipation phenotypes, including stool parameters and histopathological structure, were detected in 16-week-old C3 KO mice compared to those of wild type (WT) mice. Fecal microbiota of C3 KO mice exhibited decreases in Anaerocolumna, Caecibacterium, Christensenella, Kineothrix, and Oscillibacter populations and increases in Prevotellamassilia, Reuthenibacterium, Prevotella, Eubacterium, Culturomica, Bacteroides, and Muribaculum populations. In FMT study, key ... 전체 초록 보기

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      UCI(KEPA) : I410-ECN-0101-2021-528-001570135