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논문 기본 정보

자료유형
학술저널
저자정보
이성호 (Sungkyunkwan University School of Medicine) 김병진 (성균관대학교) 강정규 (성균관대학교) 서대철 (성균관대학교) 이승재 (성균관대학교)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.35 No.34
발행연도
2020.1
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1 - 10 (10page)

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Background: The relationship between self-reported and urinary cotinine-verified smoking status and atrial arrhythmia (AA) is unclear. The aim of this study was to evaluate the association of self-reported and urine cotinine-verified smoking status with AA. Method: A total of 201,788 participants (106,375 men, mean age 37 years) who had both a urinary cotinine measurement and electrocardiogram were included. Cotinine-verified current smoking was defined as a urinary cotinine level above 50 ng/mL. Individuals were divided into three groups based on self-reported smoking and two groups based on cotinine verified smoking status. Results: Among overall subjects, 505 had documented AA (0.3%) and 135 had atrial fibrillation (AF) (0.1%). Self-reported current smoking was associated with an increased risk of AA (odds ratio [OR], 1.42; 95% confidence interval [CI], 1.06–1.91; P = 0.019) and AF (OR, 2.20; 95% CI, 1.24–3.90; P = 0.007), whereas self-reported former smoking had no significant association with AA (OR, 1.30; 95% CI, 0.97–1.73; P = 0.078) and AF (OR, 1.74; 95% CI, 1.00–3.04; P = 0.051). Cotinine-verified current smoking showed no significant association with AA (OR, 1.24; 95% CI, 0.98–1.58; P = 0.080) and AF (OR, 1.20; 95% CI, 0.79–1.83; P = 0.391). Conclusion: Self-reported current smoking was associated with AA and AF, while self- reported former smoking and cotinine-verified current smoking showed no significant association with AA and AF.

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