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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
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- 1 - 15 (15page)
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Background: Chemoprophylaxis has been used to prevent malaria among soldiers and secondary transmission, as it effectively facilitates a decline in disease occurrence and secondary prevention. However, poor compliance and decreased risk of exposure to malaria necessitate that control strategies be reestablished. Methods: To predict the incidence of malaria according to a control strategy, we proposed a mathematical model for its transmission using epidemiological data from 2010 to 2012. The benefit component included in the analyses was the averted cost with each control strategy, and the cost components were the cost of implementing chemoprophylaxis and early diagnosis. Results: The chemoprophylaxis regimen with hydroxychloroquine sulfate and primaquine was Intervention 1, the regimen with primaquine only was Intervention 2, and diagnosis with a rapid diagnostic test (RDT) kit within 5 days of fever was Intervention 3. The simulation indicated that the combined control program with chemoprophylaxis and early diagnosis would be the most effective strategy, whereas sole early diagnosis would be the least effective strategy. However, the cost-benefit ratio of chemoprophylaxis was less than Intervention 1, irrespective of the varying range of chemoprophylaxis compliance, and that of early diagnosis was more than Intervention 1, regardless of the varying early diagnosis rate and demand for the RDT kit. Although chemoprophylaxis would be more effective at reducing the incidence of malaria than early diagnosis, it is less economical due to the higher cost. Conclusion: Our results support the introduction of early diagnosis with a RDT kit to control malaria in the Republic of Korea Army.
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참고문헌 (27)
참고문헌 신청
Fritz RF / 1953 / Imported and indigenous malaria in the United States, 1952 / Am J Trop Med Hyg 2(3):445~456
Joon-Sup Yeom / 2005 / Evaluation of Anti-Malarial Effects of Mass Chemoprophylaxis in the Republic of Korea Army / Journal of Korean Medical Science 20(5):707~712
Greenwood B / 2004 / The use of anti-malarial drugs to prevent malaria in the population of malaria-endemic areas / Am J Trop Med Hyg 70(1):1~7
박재원 / 2009 / Plasmodium vivax Malaria: Status in the Republic of Korea Following Reemergence / The Korean Journal of Parasitology 47:39~50
Mueller I / 2009 / Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite / Lancet Infect Dis 9(9):555~566
Joon-Sup Yeom / 2005 / Evaluation of Anti-Malarial Effects of Mass Chemoprophylaxis in the Republic of Korea Army / Journal of Korean Medical Science 20(5):707~712
Greenwood B / 2004 / The use of anti-malarial drugs to prevent malaria in the population of malaria-endemic areas / Am J Trop Med Hyg 70(1):1~7
박재원 / 2009 / Plasmodium vivax Malaria: Status in the Republic of Korea Following Reemergence / The Korean Journal of Parasitology 47:39~50
Mueller I / 2009 / Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite / Lancet Infect Dis 9(9):555~566
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