Time-lapse imaging of sentinel lymph node using indocyanine green with near-infrared fluorescence imaging in early endometrial cancer

최현진; 김태중; 이유영; 이정원; 김병기; 배덕수

추천

검색

자료유형: 학술저널

저자정보: 최현진 (성균관대학교 의과대학) 김태중 (성균관대학교) 이유영 (삼성서울병원) 이정원 (삼성서울병원) 김병기 (성균관대학교) 배덕수 (성균관대학교)

저널정보: 대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.27 No.3

발행연도: 2016.1

수록면: 1 - 2 (2page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Objective: Indocyanine green with near-infrared fluorescence imaging (NIR-ICG) is a newtracer modality in the limelight used for lymphatic mapping. The advantage of this methodis to provide real-time image during surgery. To use ICG for image guided lymph nodedissection, a surgeon needs to know initial appearing time and duration. Methods: A 52-year-old woman undertook surgery diagnosed with endometrial cancer. Shehad no past medical history and her body mass index was 25.3 kg/m2. Preoperative magneticresonance imaging examination revealed 2.7 cm sized cancerous mass in the endometrialcavity with superficial myometrial invasion without lymph node enlargement. Four mL(1.25 mg/mL) of ICG solution was prepared for injection. For each site, 1 mL of solution wasinjected superficially, 2–3 mm into the cervical submucosa and another 1 mL was injecteddeep, 1–2 cm into the stroma of the cervix [1,2]. We recorded video with 30° 10 mm scopeequipped with a specific lens and light source emitting both visible and NIR light (KARLSTORZ GmbH & Co. KG, Tuttlingen, Germany). Results: Pelvic lymph node was visualized from around 5 minutes. ICG was dispersed intoorgans after hysterectomy (53 minutes after ICG injection), yet we could clearly identifysentinel lymph node (SLN). Pathology revealed endometriod adenocarcinoma grade I,myometrial invasion with less than half of myometrium and no lymph node metastasis. Conclusion: Cervical injection of ICG provides good visualization of SLN from 5 minutes toover an hour. Our film gives an idea about time management to make a plan for surgery andnot to miss SNLs.

참고문헌 (2)

참고문헌 신청

Abu-Rustum NR / 2009 / Sentinel lymph node mapping for grade 1 endometrial cancer: is it the answer to the surgical staging dilemma? / Gynecol Oncol 113:163~169

How J / 2015 / Comparing indocyanine green, technetium, and blue dye for sentinel lymph node mapping in endometrial cancer / Gynecol Oncol 137:436~442

이 논문의 저자 정보

최현진

소속기관 성균관대학교

주요연구분야 의약학 > 임상의학 > 산부인과학

논문수 2 이용수 0

김태중

소속기관 삼성서울병원