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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.9
- 수록면
- 196 - 204 (9page)
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초록· 키워드
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Nineteen compounds, including one organic acid (1), one anthraquinone (2), one amide (3), and sixteen triterpenoid saponins (4 - 19) were isolated from the leaves of Acanthopanax henryi (Oliv.) Harms (Araliaceae). Their structures were determined on the basis of physicochemical properties and spectral analyses (HR-MS and NMR). Among them, compounds 2, 3, 7, 12 and 19 were new within Araliaceae. Compounds 4, 5, 9 - 11, 13, 14, 16 and 18 were reported for the first time from the Acanthopanax genus. Except for compounds 4 and 9, other compounds were isolated from A. henryi (Oliv.) Harms for the first time. The rare anthraquinone, compound 2, significantly decreased the production of NO and the levels of other inflammatory factors, such as TNF-α and IL-6, in lipopolysaccharide (LPS)-stimulated macrophages in a dose-dependent manner. This is the first time to report anti-inflammatory effect of this compound.
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참고문헌 (21)
참고문헌 신청
1978 / Flora Reipublicae Popularis Sinicae / Science Press :102
Yook, C. S / 2001 / Medicinal Herbs of Acanthopanax in Asia / Kyung-Won Media :132~145
Hunan Food and Drug Administration / 2009 / Hunan local medicinal materials standard / Hunan Science and Technology Press
Zhang, X. D / 2013
Li, G. Z / 2013 / Chinese Traditional and Herbal Drugs 44:808~811
Yook, C. S / 2001 / Medicinal Herbs of Acanthopanax in Asia / Kyung-Won Media :132~145
Hunan Food and Drug Administration / 2009 / Hunan local medicinal materials standard / Hunan Science and Technology Press
Zhang, X. D / 2013
Li, G. Z / 2013 / Chinese Traditional and Herbal Drugs 44:808~811
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