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논문 기본 정보

자료유형
학술저널
저자정보
조준영 (울산대학교 서울아산병원 마취통증의학과) 윤정필 (양산부산대학교병원 마취통증의학과) 장희윤 (Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine) 김욱종 (울산대학교 아산병원 마취통증의학과) Seung-Woo Ku (Department of Anesthesiology and Pain Medicine, University of Ulsan College of Medicine) 최성수 (울산대학교)
저널정보
대한중환자의학회 Acute and Critical Care Acute and Critical Care Vol.39 No.1
발행연도
2024.2
수록면
61 - 69 (9page)
DOI
10.4266/acc.2022.01543

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Background: Although preoxygenation is an essential procedure for safe endotracheal intubation, in some cases securing sufficient time for tracheal intubation may not be possible. Patients with head and neck cancer might have a difficult airway and need a longer time for endotracheal intubation. We hypothesized that the extended apneic period with preoxygenation via a high-flow nasal cannula (HFNC) is beneficial to patients who undergo head and neck surgery compared with preoxygenation with a simple mask. Methods The study was conducted as a single-center, single-blinded, prospective, randomized controlled trial. Patients were divided into groups based on one of the two preoxygenation methods: HFNC group or simple facemask (mask group). Preoxygenation was performed for 5 minutes with each method, and endotracheal intubation for all patients was performed using a video laryngoscope. Oxygen partial pressures of the arterial blood were compared at the predefined time points.Results: For the primary outcome, the mean arterial oxygen partial pressure (PaO2) immediately after intubation was 454.2 mm Hg (95% confidence interval [CI], 416.9–491.5 mm Hg) in the HFNC group and 370.7 mmHg (95% CI, 333.7–407.4) in the mask group (P=0.002). The peak PaO2 at T2 was not statistically different between the groups (P=0.355).Conclusions: Preoxygenation with a HFNC extending to the apneic period before endotracheal intubation may be beneficial in patients with head and neck cancer.

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