지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
ATF2 is a cellular transcription factor which belongs to the CREB/ATF class and it is leucine zipper protein which generally binds to DNA as dimers. This paper presents the procedure for subcloning the ATF2 gene and the results of experiment used the expressed ATF2. The pET expression vector was used since it produced 6xHis fusion protein for easy purification using affinity column. The Nickel chelating chromatography was used for purifying the expressed ATF2 from E. coli BL21. Subsequently In vitro binding pull-down assay showed the binding specificity of ATF2 with AP-1 family factors such as BATF, c-Fos, c-Jun and ATF2 itself. ATF2 forms homodimer as well as strong heterodimer with BATF. It also forms stable dimer with c-Jun but barely binds with c-Fos.
목차
Abstract
실험재료 및 방법
결과 및 고찰
요약
감사의 글
참고문헌
References
참고문헌 (26)
참고문헌 신청
Abate, C., L. Patel, F. J. Rauscher and T. Curran. 1990. Redox regulation of fos and jun DNA-binding activity in vivo. Science 249, 1157-1161.
Angel, P., M. Imagawa, R. Chiu, B. Stein, R.J. Imbra, H. J. Rahmsdorf, C. Jonat, P. Herrlich and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49, 729-739.
Blank, V. and N. C. Andrews. 1997. The Maf transcription factors: regulators of differentiation. Trends Biochem Sci 22, 437-441.
Cantley, L. C., K. R. Auger, C. Carpenter, B. Duckworth, A. Graziani, R. Kapeller, and S. Soltoff. 1991. "Oncogenes and signal transduction." Cell, 64, 281-302.
Cowell, I. G. 2002 . E4BP4/NFIL3, a PAR-related bZIP factor with many roles. Bioessays 24, 1023-1029.
Angel, P., M. Imagawa, R. Chiu, B. Stein, R.J. Imbra, H. J. Rahmsdorf, C. Jonat, P. Herrlich and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49, 729-739.
Blank, V. and N. C. Andrews. 1997. The Maf transcription factors: regulators of differentiation. Trends Biochem Sci 22, 437-441.
Cantley, L. C., K. R. Auger, C. Carpenter, B. Duckworth, A. Graziani, R. Kapeller, and S. Soltoff. 1991. "Oncogenes and signal transduction." Cell, 64, 281-302.
Cowell, I. G. 2002 . E4BP4/NFIL3, a PAR-related bZIP factor with many roles. Bioessays 24, 1023-1029.
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
SIRT1 Suppresses Activating Transcription Factor 4 (ATF4) Expression in Response to Proteasome Inhibition
Journal of Microbiology and Biotechnology
2013 .01
-
Curcumin Inhibits Cell Proliferation of Human Colorectal HCT116 Cells through Up-Regulation of Activating Transcription Factor 3 (ATF3)
생명과학회지
2012 .04
-
ATF3를 통한 caffeic acid phenethyl ester에 의한 NAG-1 유전자의 발현 증가
생명과학회지
2018 .01
-
Development of a Chimera Molecule, GFP-ATF6 to monitor Stress-Condition of Cells in vitro
한국생명과학회 심포지움
2006 .04
-
Upregulation of ATF3 Stimulates Production of Cytokine during Streptococcus pneumoniae Infection
한국미생물학회 학술대회논문집
2014 .04
-
Transcription of the protein kinase C-δ gene is activated by JNK through c-Jun and ATF2 in response to the anticancer agent doxorubicin
Experimental and Molecular Medicine
2008 .01
-
Development of a Reporter System Monitoring Regulated Intramembrane Proteolysis of the Transmembrane bZIP Transcription Factor ATF6α
Molecules and Cells
2019 .01
-
The transcription factor Batf3 inhibits the differentiation of regulatory T cells in the periphery
Experimental and Molecular Medicine
2017 .01
-
Eukaryotic Stress Response Gene ATF3 Provides Protection from Staphylococcus aureus and Listeria monocytogenes Infections
한국미생물학회 학술대회논문집
2016 .04
-
Atf1 and Pcr1, Stress-Responsive Transcription Factors, Are Required for Heterochromatin Silencing from Schizosaccharomyces pombe
한국동물학회 학술대회
2001 .01
-
EGCG, genistein, resveratrol 처리에 의한 ATF3와 NAG-1 유전자 발현변화의 p53 의존성 분석
생명과학회지
2018 .05
-
Expression, Purification, and Biological Characterization of The Amino-Terminal Fragment of Urokinase in Pichia pastoris
Journal of Microbiology and Biotechnology
2013 .01
-
Enhancing the Solubility of Recombinant Akt1 in Escherichia coli with an Artificial Transcription Factor Library
Journal of Microbiology and Biotechnology
2006 .01
-
Differential inhibition of endothelial cell proliferation and migration by urokinase subdomains: amino-terminal fragment and kringle domain
Experimental and Molecular Medicine
2003 .01
-
아크 이온 플레이팅 공정 조건에 따른 핵연료 피복관용 내산화막 고온산화 특성 분석
한국진공학회 학술발표회초록집
2019 .08
-
Effects of Ceramide on c-fos and c-jun Gene Expression during Differentiation of U-937 Cells.
한국동물학회 학술대회
1994 .01
-
Induction of unfolded protein response during neuronal induction of rat bone marrow stromal cells and mouse embryonic stem cells
Experimental and Molecular Medicine
2009 .01
-
소포체스트레스 센서 OASIS family의 분자기전
생명과학회지
2015 .04
-
Heterodimeric AP-1 of c-Jun and c-Fos Mediates Activin Signaling During Xenopus Development
한국생명과학회 심포지움
2006 .04
-
오미자 박 추출물 및 schizandrin에 의한 암세포 항성장 및 세포사멸 활성
생명과학회지
2018 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-470-015375936