메뉴 건너뛰기
소속 기관 / 학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
고객센터 ENG
주제분류

논문 기본 정보

저자정보
저널정보
대한의생명과학회 대한의생명과학회지 대한의생명과학회지 제11권 제3호
오류 신고하기

피인용 0

검색

    초록·키워드

    Resent studies have reported increased isolation of extended-spectrum β-lactamase (ESBL) producing strains at sevearal hospital in Korea. We studied to investigate the isolation rates of ESBL strains from clinical isolates of Klebsiella pneumoniae and to characterize differences in types using analyses of genotyping and antibiotic susceptibility test. Antibiotic susceptibility test with confirmation of ESBL by double disk synergy test was performed on the 54 ESBL strains of Klebsoella pneumoniae from a hospital in Busan. Transfer of resistant gene in ESBL strains resistant to 3rd generated antibiotics was confirmed by transconjugation test using E. coli RG176<sup>nalⓡ</sup>. blaTEM, blaSHV, blaCTX-M genes were detected by PCR. ESBL producing strains had 100% of resistant rate to ampicillin, azteronam, cefazolin, cefepime and ceftriaxone (β-lactam antibiotics). Forty strains of bla TEM (74%), 41 strains of bla SHV (76%), 23 strains of bla CTX-M (43%) were found, respectively, The strains had one or more genes. They had high resistant rates to β-lactam antibiotics including cephalosporin. The resistant rates of strains with multiple resistant genes were higher than those of strains with single resistant gene.

    최근 본 자료 전체보기

      UCI(KEPA) : I410-ECN-0101-2009-510-017356745