인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
It is demonstrated that cadmium has cytotoxic effect on glial cells, oxygen radicals are involved in cadmium-induced cytotoxicity. However, the toxic mechanism of cadmium is left unknown so far. The purpose of this study was to examine the cytotoxicity of CdCl<SUB>2</SUB> on C<SUB>6</SUB> glioma cells. The cytotoxicy was measured by cell viability via XTT assay in C<SUB>6</SUB> glioma cells. Colorimetric assay such as XTT assay is regarded as a very sensitive screening method for the determination of the cell viability on a lots of chemicals. In this study, CdCl<SUB>2</SUB> decreased cell viability according to the dose- and time dependent manners after C<SUB>6</SUB> glioma cells were treated with various concentrations of CdCl<SUB>2</SUB> for 48 hours. IC<SUB>90</SUB> and IC<SUB>50</SUB> values for XTT assay was determined at 5 μM and 55 μM of CdCl<SUB>2</SUB>, respectively. These results suggest that CdCl<SUB>2</SUB> has highly cytotoxic effect on C<SUB>6</SUB> glioma cells by the decrease of cell viability.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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UCI(KEPA) : I410-ECN-0101-2009-510-017357404