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자료유형
학술저널
저자정보
저널정보
한국식물병리학회 The Plant Pathology Journal The Plant Pathology Journal Vol.17 No.2
발행연도
2001.4
수록면
77 - 82 (6page)

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초록· 키워드

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Erwinia amylovora causes a devastating disease called fire blight in rosaceous trees and shrubs such as apple, pear, and raspberry. To successfully infect its hosts, the pathogen requires a set of clustered genes termed hrp. Studies on the hrp system of E. amylovora indicated that it consists of three functional classes of genes. Regulation genes including hrpS, hrpXY, and hrpL produce proteins that control the expression of other genes in the cluster. Secretion genes, many of which named hrc, encode proteins that may form a transmembrane complex, which is devoted to type Ⅲ protein secretion. Finally, several genes encode the proteins that are delivered by the protein secretion apparatus. They include harpins, DspE, and other potential effector proteins that may contribute to proliferation of E. amylovora inside the hosts. Harpins are glycine-rich heat-stable elicitors of the hypersensitive response, and induce systemic acquired resistance. The pathogenicity protein DspE is homologous and functionally similar to an avirulence protein of Pseudomonas syringae. The region encompassing the hrpldsp gene cluster of E. amylovora shows features characteristic of a genomic island: a cryptic recombinase/integrase gene and a tRNA gene are present at one end and genes corresponding to those of the Escherichia coli K-12 chromosome are found beyond the region. This island, designated the Hrp pathogenicity island, is more than 60 kilobases in size and carries as many as 60 genes.

목차

Fire Blight and Erwinia amylovora
Hypersensitive Reaction and hrp Genes
Hrp Pathogenicity Island
Regulation of hrp Gene Expression
Hrp Type Ⅲ Protein Secretion
Harpins: Hrp-secreted HR Elicitors
DspE: a Pathogenicity/Avirulence Effector Protein
A Phytotoxin Produced by E. amylovora?
Future Directions
References

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