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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.9
- 수록면
- 333 - 340 (8page)
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In recent years there have been renewed interests in the use of air ionization to control the spread of airborne infection and malodor. An ion cluster is a group of 10-60 oxygen molecules. Clustered ions tend to bundle up microbes, germs and fungi. Deodorization and sterilization are achieved through those characteristics. The ion cluster turns back into a simple oxygen molecule status due to the ion equilibrium in 120 seconds. However, it remains unclear whether clustered ions are safe or not for physical and biological mechanisms. A study was, therefore, undertaken to determine the safety associated with common use of the IonCluster<SUP>®</SUP> (SUDO Premium Engineering Co., Ltd.). We installed the IonCluster<SUP>®</SUP> in supply duct of one individual ventilated cages (IVC) rack for test groups. And the animals were analyzed for body weighing, water intakes, food intakes, blood pressure, heart rate, organ weight, histopathology (cornea, trachea and lung), hematology and blood chemistry in 11 and 22 weeks, control versus treatment groups. Food intake in 9 weeks old IonCluster<SUP>®</SUP>-treated females was significantly lower than controls. Water intakes were significantly increased in 11, 18 and 19 weeks old IonCluster<SUP>®</SUP>-treated males, compared to those of controls. The levels of alkaline phosphatase in male mice and phosphorus in female mice were significantly lower than controls. There were no considerable treatment-related changes in the body weights and absolute organ weights except for the decrease in the weight of left adrenal gland of IonCluster<SUP>®</SUP>-treated males. In addition, no meaningful changes in the histopathological findings of target organs were observed in treatment groups compared to controls. This study demonstrates that IonCluster<SUP>®</SUP> does not cause any toxicological signs, and has safety by newly developed deodorizer of the air in the laboratory animal facility.
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