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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.16 No.1
- 발행연도
- 2011.3
- 수록면
- 89 - 94 (6page)
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초록· 키워드
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The potential biological activities of water and ethanol extracts from two varieties of Rubus coreanus Miquel fruits produced in the Gochang-gun (GR) and Hoengseong-gun (HR) regions of Korea were examined. The hydroxyl radical ( OH) scavenging activity, reducing power, lipid peroxidation inhibitory activity, and antiproliferative activity on cancer cells by these extracts were examined, and α-amylase and α-glucosidase inhibition assays were also performed. The EtOH extract from GR showed high hydroxyl radical scavenging activity (EC<SUB>50</SUB>=119.47±5.13 ㎍/mL), lipid peroxidation inhibitory activity (EC<SUB>50</SUB>=213.45±3.14 ㎍/mL) and a concentration dependence, with OD values ranging from 0.15 to 0.56 (50 to 200 ㎍/mL), for reducing power. The EtOH extract from GR has the highest antiproliferative activities on MDA-MB-231 and HepG2 cancer cells among four extracts. Meanwhile, all extracts showed certain α-amylase and α-glucosidase inhibition activities. These results indicate that extracts from two varieties of R. coreanus fruits have significant antioxidant, anti-diabetic and anti-tumorigenic activities, which suggest these extracts could be a potential source for pharmaceutical.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
CONCLUSION
REFERENCES
참고문헌 (26)
참고문헌 신청
1. [학술지(정기간행물)] - Liu JK / 2002 / Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-L-carnitine and /or R-α-lipoic acid / Proc Natl Acad Sci USA 99 : 2356 ~ 2361
2. [학술지(정기간행물)] - Jae-Kwan Hwang / 2006 / Antioxidant Properties of Tannic Acid and its Inhibitory Effects on Paraquat-Induced Oxidative Stress in Mice / Food Science and Biotechnology 15 (5) : 728 ~ 734
3. [학술지(정기간행물)] - 김길남 / 200607 / Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava / FOOD AND CHEMICAL TOXICOLOGY 44 : 1065 ~ 1074
4. [학술지(정기간행물)] - Headig D / 2008 / Identification of a xylosyltransferase II gene haplotype marker for diabetic nephropathy in type 1 diabetes / Clin Chim Acta 398 : 90 ~ 94
5. [학술지(정기간행물)] - Jain S / 2008 / Type 2 diabetes mellitus－its global prevalence and therapeutic strategies / Diab Met Syndr Clin Res Rev 79 : 14 ~ 27
2. [학술지(정기간행물)] - Jae-Kwan Hwang / 2006 / Antioxidant Properties of Tannic Acid and its Inhibitory Effects on Paraquat-Induced Oxidative Stress in Mice / Food Science and Biotechnology 15 (5) : 728 ~ 734
3. [학술지(정기간행물)] - 김길남 / 200607 / Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava / FOOD AND CHEMICAL TOXICOLOGY 44 : 1065 ~ 1074
4. [학술지(정기간행물)] - Headig D / 2008 / Identification of a xylosyltransferase II gene haplotype marker for diabetic nephropathy in type 1 diabetes / Clin Chim Acta 398 : 90 ~ 94
5. [학술지(정기간행물)] - Jain S / 2008 / Type 2 diabetes mellitus－its global prevalence and therapeutic strategies / Diab Met Syndr Clin Res Rev 79 : 14 ~ 27
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UCI(KEPA) : I410-ECN-0101-2012-511-004225915