인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.11
- 수록면
- 259 - 266 (8page)
이용수
초록· 키워드
??The current study examined the effect of quercetin supplements on the lipid-lowering and antioxidant metabolism in ethanol-fed rats, The control group(E<sub>8</sub>) received ethanol only diet for 8 wks, whereas the other group(E<sub>8</sub>Q<sub>4</sub>) received a diet including quercetin supplementation(0.05%, wt/wt) for 4 wks while on the ethanol diet for 8wks. The hepatic alcohol dehydrogenase activity was significantly higher in the E<sub>8</sub>Q<sub>4</sub> group than in the E<sub>8</sub> group. Supplementation with quercetin significantly elevated the HDL- cholesterol concentration, the HDL-C/total-C ratio, and lowered the atherogenic index(AI) compared to the E<sub>8</sub> group. The hepatic triglyceride and cholesterol contents were significantly lowered by the quercetin supplement compared to those of the control group. The hepatic HMG-CoA reductase and ACAT activities of the E<sub>8</sub>Q<sub>4</sub>group were significantly lower than those of the E<sub>8</sub> group. The overall potential for antioxidant defense was significantly enhanced by the quercetin supplement, as indicated by a decrease in plasma and hepatic TBARS levels. The hepatic GSH-Px and G6PD activities were significantly higher in theE<sub>8</sub>Q<sub>4</sub> group compared to the E<sub>8</sub> group. The current results suggest that dietary quercetin leads to the inhibition of HMG-CoA reductase and ACAT, which in turn lowers cholesterol levels and normalizes antioxidant enzyme activities.
상세정보 수정요청해당 페이지 내 제목·저자·목차·페이지정보가 잘못된 경우 알려주세요!
목차
- INTRODUCTION
- MATERIALS AND METHODS
- RESULTS
- DISCUSSION
- Literature Cited
참고문헌
참고문헌 신청최근 본 자료
UCI(KEPA) : I410-ECN-0101-2012-594-004194285
