지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.16 No.3
- 발행연도
- 2011.9
- 수록면
- 248 - 252 (5page)
이용수
초록· 키워드
오류제보하기
Soy protein based formula (SPF) has been developed for infants who are at a high risk for atopic dermatitis (AD) and cow’s milk protein allergy (CMA). We performed this study to evaluate the therapeutic efficacy and safety of SPF compared to conventional hydrolyzed cow’s milk formula (hCMF) in the feeding of infants with AD and CMA. 38 infants (12 to 24 months of age) diagnosed with CMA and AD were randomized to receive either SPF or hCMF for 12 weeks. Follow-up was conducted at 4, 8 and 12 weeks. Growth parameters of the infants were evaluated during each visit. Clinical evaluations, including AD severity scores, pruritus, specific immunoglobulin E (IgE) (cow’s milk protein and soy protein) levels of peripheral blood, were made at enrollment and week 12. Analysis was performed on the 32 infants (SPF: n=16, hCMF: n=16) who completed the 12-week intervention. Eczema area and severity index (EASI) scores, a measure of the severity of AD, and pruritus were significantly reduced after 12 weeks compared to enrollment in the both groups; however, the median changes for EASI scores and pruritus were not statistically different between the two groups. The growth parameters did not differ significantly between both groups at any assessed time point. This study suggests that SPF could be useful in decreasing the severity of AD without affecting infant growth status. Therefore SPF could provide an adequate and safe alternative to hCMF in treating infants with AD and CMA during the first 12 to 24 months of their life.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ABBREVIATIONS
ACKNOWLEDGMENTS
REFERENCES
참고문헌 (23)
참고문헌 신청
1. [학술지(정기간행물)] - Moore MM / 2004 / Perinatal predictors of atopic dermatitis occurring in the first six months of life / Pediatrics 113 : 468 ~ 474
2. [학술지(정기간행물)] - Greer FR / 2008 / Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas / Pediatrics 121 : 183 ~ 191
3. [학술지(정기간행물)] - Bieber T / 2008 / Atopic dermatitis / N Engl J Med 358 : 1483 ~ 1494
4. [학술지(정기간행물)] - Eichenfield LF / 2003 / Consensus conference on pediatric atopic dermatitis / J Am Acad Dermatol 49 : 1088 ~ 1095
5. [학술지(정기간행물)] - Hahn EL / 2005 / The atopic march: the pattern of allergic disease development in childhood / Immunol Allergy Clin North Am 25 : 231 ~ 246
2. [학술지(정기간행물)] - Greer FR / 2008 / Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas / Pediatrics 121 : 183 ~ 191
3. [학술지(정기간행물)] - Bieber T / 2008 / Atopic dermatitis / N Engl J Med 358 : 1483 ~ 1494
4. [학술지(정기간행물)] - Eichenfield LF / 2003 / Consensus conference on pediatric atopic dermatitis / J Am Acad Dermatol 49 : 1088 ~ 1095
5. [학술지(정기간행물)] - Hahn EL / 2005 / The atopic march: the pattern of allergic disease development in childhood / Immunol Allergy Clin North Am 25 : 231 ~ 246
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UCI(KEPA) : I410-ECN-0101-2013-511-000751805