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논문 기본 정보

자료유형
학술저널
저자정보
Hye-Bin Yeo (고려대학교) Ho-Kyoung Yoon (고려대학교) Heon-Jeong Lee (고려대학교) Seung-Gul Kang (가천대학교) Ki-Young Jung (고려대학교) Leen Kim (고려대학교)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.36 No.2
발행연도
2012.4
수록면
190 - 197 (8page)

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초록· 키워드

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Ginseng has a long history of use for health enhancement, and there is some evidence from animal studies that it has a benefi cial effect on cognitive performance. The purpose of this study was to investigate the effect of Korean red ginseng on cognitive performance in humans. A total of 15 healthy young males with no psychiatric or cognitive problems were selected based on an interview with a board-certifi ed psychiatrist. The subjects were randomly assigned to receive a daily dose of 4,500 mg red ginseng or placebo for a 2-week trial. There were 8 subjects in the red ginseng group and 7 subjects in the placebo group. All of the subjects were analyzed with the Vienna test system and a P300 event-related potential (ERP) test. There were no signifi cant differences in the Vienna test system scores between the red ginseng group and the placebo group. In the event-related potential test, the C3 latency of the red ginseng group tended to decrease during the study period (p=0.005). After 2 wk, signifi cant decreases were observed in the P300 latencies at Cz (p=0.008), C3 (p=0.005), C4 (p=0.002), and C mean (p=0.003) in the red ginseng group. Our results suggest that the decreased latency in ERP is associated with improved cognitive function. Further studies with a higher dosage of ginseng, a larger sample size, and a longer follow-up period are necessary to confi rm the clinical effi cacy of Korean red ginseng.

목차

INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES

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