지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.10
- 수록면
- 271 - 275 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: Whereas the Kasai portoenterostomy (KPE) is an accepted first line of surgery for bile drainage in infants with biliary atresia, its long-term effectiveness is not clear because its etiology and pathogenesis remains unknown. This study was aimed to investigate the late complications occurring in long-term survivors and the current status of living patients who survived over 10 years after KPE. Methods: A retrospective analysis of the medical records of 32 patients who underwent KPE from 1990 to 2000 was done. We analyzed 10-year survival rates with the Kaplan-Meier method and the current status of the long-term survivors. Results: The overall 10-year survival rate by Kaplan-Meier method after KPE was 76.2%. Eight (25%) patients had died, including 4 who were transplanted. Nineteen (59.4%) patients survived over 10 years. Among them, 6 (31.6%) patients had portal hypertension, and 5 (26.3%) had episodes of cholangitis. Two had intrahepatic cyst and 2 had intestinal obstruction. Six (31.6%) patients have been well without any complications. Conclusion: The long-term survival rate of biliary atresia is slightly improving. However, two thirds of patients suffer from various complications. One-third of survivors go on without any complication. As biliary atresia is known as a progressive inflammatory disease, careful life-long follow- up is needed in long-term survivals after KPE.
목차
Purpose
INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (16)
참고문헌 신청
1. [학술지(정기간행물)] - Shinkai M / 2009 / Long-term outcome of children with biliary atresia who were not transplanted after the Kasai operation: >20-year experience at a children's hospital / J Pediatr Gastroenterol Nutr 48 : 443 ~ 450
2. [학술지(정기간행물)] - Hadzić N / 2003 / Long-term survival following Kasai portoenterostomy: is chronic liver disease inevitable / J Pediatr Gastroenterol Nutr 37 : 430 ~ 433
3. [학술지(정기간행물)] - Hartley JL / 2009 / Biliary atresia / Lancet 374 : 1704 ~ 1713
4. [학술지(정기간행물)] - Leonhardt J / 2011 / Biliary atresia: lessons learned from the voluntary German registry / Eur J Pediatr Surg 21 : 82 ~ 87
5. [학술지(정기간행물)] - Altman RP / 1997 / A multivariable risk factor analysis of the portoenterostomy (Kasai) procedure for biliary atresia: twenty-five years of experience from two centers / Ann Surg 226 : 348 ~ 353
2. [학술지(정기간행물)] - Hadzić N / 2003 / Long-term survival following Kasai portoenterostomy: is chronic liver disease inevitable / J Pediatr Gastroenterol Nutr 37 : 430 ~ 433
3. [학술지(정기간행물)] - Hartley JL / 2009 / Biliary atresia / Lancet 374 : 1704 ~ 1713
4. [학술지(정기간행물)] - Leonhardt J / 2011 / Biliary atresia: lessons learned from the voluntary German registry / Eur J Pediatr Surg 21 : 82 ~ 87
5. [학술지(정기간행물)] - Altman RP / 1997 / A multivariable risk factor analysis of the portoenterostomy (Kasai) procedure for biliary atresia: twenty-five years of experience from two centers / Ann Surg 226 : 348 ~ 353
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UCI(KEPA) : I410-ECN-0101-2013-514-002683754