지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.5
- 수록면
- 281 - 287 (7page)
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초록· 키워드
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Purpose: Clinical outcomes of papillary thyroid microcarcinoma (PTMC) vary. In general, age at diagnosis is an independent prognostic factor in conventional papillary thyroid carcinoma. However, it is unclear in patients of PTMC. The purpose of this study was to identify clinicopathologic features and prognostic factors of PTMC according to patients’ age. Methods: Five hundred twenty-seven patients who received thyroid surgery and diagnosed as having PTC between January 2001 and December 2009 were included. The clinical data were retrospectively analyzed. Results: We divided the patients into two groups; group Ⅰ who were younger than 45 years, and group Ⅱ who were 45 years old or older. The mean tumor size and incidences of neck lymph nodes involvement of group I was larger than group Ⅱ. In group Ⅱ, however, there were more patients who had multiple cancer foci and were body mass index ≥ 25 ㎏/㎡. The overall incidence of recurrent disease was 3.2%. The incidence of recurrence was higher in group Ⅱ (2.0% vs. 4.0%), without a statistical difference. In multivariate analysis, the significant risk factors of recurrence were male gender and multifocality in group Ⅰ, and lymph node metastasis and multifocality in group Ⅱ. In particular, the male gender and multifocality showed the highest odds ratio (OR) on each group (OR, 4.721 and 6.177). Conclusion: The patients with PTMCs had different clinical features and prognostic factors according to age. Hence, clinicians should consider a different strategy for therapy and plan for follow-up according to age.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONFLICTS OF INTEREST
REFERENCES
참고문헌 (31)
참고문헌 신청
1. [단행본] - DeLellis RA / 2004 / Pathology and genetics of tumours of endocrine organs, World Health Organization classification of tumours; v. 8 / IARC Press
2. [학술지(정기간행물)] - Ito Y / 2003 / An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid / Thyroid 13 : 381 ~ 387
3. [학술지(정기간행물)] - Chow SM / 2003 / Papillary microcarcinoma of the thyroid－Prognostic significance of lymph node metastasis and multifocality / Cancer 98 : 31 ~ 40
4. [학술지(정기간행물)] - Bramley MD / 1996 / Papillary microcarcinoma of the thyroid gland / Br J Surg 83 : 1674 ~ 1683
5. [학술지(정기간행물)] - Franssila KO / 1986 / Occult papillary carcinoma of the thyroid in children and young adults / Cancer 58 : 715 ~ 719
2. [학술지(정기간행물)] - Ito Y / 2003 / An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid / Thyroid 13 : 381 ~ 387
3. [학술지(정기간행물)] - Chow SM / 2003 / Papillary microcarcinoma of the thyroid－Prognostic significance of lymph node metastasis and multifocality / Cancer 98 : 31 ~ 40
4. [학술지(정기간행물)] - Bramley MD / 1996 / Papillary microcarcinoma of the thyroid gland / Br J Surg 83 : 1674 ~ 1683
5. [학술지(정기간행물)] - Franssila KO / 1986 / Occult papillary carcinoma of the thyroid in children and young adults / Cancer 58 : 715 ~ 719
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UCI(KEPA) : I410-ECN-0101-2013-514-002669341