지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.2
- 수록면
- 94 - 100 (7page)
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초록· 키워드
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Purpose: Granulomatous mastitis (GM), reported for the first time by Kessler and Wolloch in 1972, is a rare and benign inflammatory lesion of the breast. The etiology of GM is currently unknown, but some reports have suggested autoimmunity. The aim of this study was to evaluate the clinical characteristic, clinical presentations and radiological features of GM.
Methods: A chart review was performed for 23 patients, with GM confirmed by a pathological examination, between July 1999 and December 2005. A retrospective review of the clinical and radiological finding, as well as the cytological results of the patients was undertaken.
Results: The ages of these patients ranged between 29 and 74 years, with a mean of 39.7 years. The median follow-up was 8 months. Twenty patients (87%) presented with a mass as the chief complaint, with a median size of 2.56 cm (range 0.78∼6.5 ㎝). Eight patients (34.8%) had radiological findings suspicious of malignancy. Tuberculosis was diagnosed using Tb-PCR in 1 patient. Twenty-two of the 23 patients underwent a wide excision, and the one remaining patient underwent incision and drainage. One of 23 patients had a recurrent disease.
Conclusion: GM is a rare breast disease, which clinically mimics cancer. As radiological imaging, such as mammography or ultrasonography, are unreliable in distinguishing GM from breast cancer, further special examinations, for example FNAB and gun biopsy, are necessary. The single most important differential diagnosis of GM is tuberculosis, especially in developing countries. We suggest that the evaluation for tuberculosis is essential for the differential diagnosis of GM using clinical and pathological methods.
Methods: A chart review was performed for 23 patients, with GM confirmed by a pathological examination, between July 1999 and December 2005. A retrospective review of the clinical and radiological finding, as well as the cytological results of the patients was undertaken.
Results: The ages of these patients ranged between 29 and 74 years, with a mean of 39.7 years. The median follow-up was 8 months. Twenty patients (87%) presented with a mass as the chief complaint, with a median size of 2.56 cm (range 0.78∼6.5 ㎝). Eight patients (34.8%) had radiological findings suspicious of malignancy. Tuberculosis was diagnosed using Tb-PCR in 1 patient. Twenty-two of the 23 patients underwent a wide excision, and the one remaining patient underwent incision and drainage. One of 23 patients had a recurrent disease.
Conclusion: GM is a rare breast disease, which clinically mimics cancer. As radiological imaging, such as mammography or ultrasonography, are unreliable in distinguishing GM from breast cancer, further special examinations, for example FNAB and gun biopsy, are necessary. The single most important differential diagnosis of GM is tuberculosis, especially in developing countries. We suggest that the evaluation for tuberculosis is essential for the differential diagnosis of GM using clinical and pathological methods.
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REFERENCES
참고문헌 (27)
참고문헌 신청
1. [학술지(정기간행물)] - Diesing D / 2004 / Granulomatous mastitis / Arch Gynecol Obstet 269 : 233 ~ 236
2. [학술지(정기간행물)] - Carmalt HL / 1981 / Granulomatous mastitis / Med J Aust 1 : 356 ~ 359
3. [학술지(정기간행물)] - Axelsen RA / 1988 / Granulomatous lobular mastitis: report of a case with previously undescribed histopathological abnormalities / Pathology 20 : 383 ~ 389
4. [학술지(정기간행물)] - Park IK / 2005 / Granulomatous mastitis / J Korean Breast Cancer Soc 8 : 64 ~ 68
5. [학술지(정기간행물)] - Lai EC / 2005 / The role of conservative treatment in idiopathic granulomatous mastitis / Breast J 11 : 454 ~ 456
2. [학술지(정기간행물)] - Carmalt HL / 1981 / Granulomatous mastitis / Med J Aust 1 : 356 ~ 359
3. [학술지(정기간행물)] - Axelsen RA / 1988 / Granulomatous lobular mastitis: report of a case with previously undescribed histopathological abnormalities / Pathology 20 : 383 ~ 389
4. [학술지(정기간행물)] - Park IK / 2005 / Granulomatous mastitis / J Korean Breast Cancer Soc 8 : 64 ~ 68
5. [학술지(정기간행물)] - Lai EC / 2005 / The role of conservative treatment in idiopathic granulomatous mastitis / Breast J 11 : 454 ~ 456
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